My newest research stream explicitly overlays kin support systems, social safety nets, and climate risk to identify inequalities between groups across geographic space. How far a person lives away from their kin determines the types and amount of help they can exchange with each other, and the generosity and effectiveness of social safety-net programs differ between states and counties. Locales also differ in their exposure to environmental and climate-related risks that may impact residents’ health and well-being. Simultaneously, residential segregation creates systemic inequalities in the geographic risk profiles by race, ethnicity, and immigration history. Developing methods that will reveal how risk and safety nets overlap in neighborhoods across the United States will uncover mechanisms for enduring health disparities and provide opportunities to design effective safety net policies.